METHANOL AND WATER EXTRACTS OF COSTUS SPECIOSUS (J.KÖNIG) SM. LEAVES REVERSE THE HIGH FAT DIET INDUCED PERIPHERAL INSULIN RESISTANCE IN EXPERIMENTAL WISTAR RATS
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Tinospora crispa Ameliorates Insulin Resistance Induced by High Fat Diet in Wistar Rats
The antidiabetic properties of Tinospora crispa, a local herb that has been used in traditional Malay medicine and rich in antioxidant, were explored based on obesity-linked insulin resistance condition. Male Wistar rats were randomly divided into four groups, namely, the normal control (NC) which received standard rodent diet, the high fat diet (HFD) which received high fat diet only, the high...
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BACKGROUND Quercetin derivatives in onions have been regarded as the most important flavonoids to improve diabetic status in cells and animal models. The present study was aimed to examine the hypoglycemic and insulin-sensitizing capacity of onion peel extract (OPE) containing high quercetin in high fat diet/streptozotocin-induced diabetic rats and to elucidate the mechanism of its insulin-sens...
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Introduction. The aim of this study was to investigate the effects of high fat diet-induced obesity and interval and continuous exercise training on visceral fat SIRT1 and insulin resistance in male rats. Method. Forty male rats were divided into two groups: high-fat diet (HFD; n=32) and standard diet (C; n=8). After 10 weeks inducing obesity, eight rats from the HFD and C groups were sacrifi...
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ABSTRACT Background and Objectives: Obesity is a global health problem that could lead to cardiovascular disease, diabetes and cancer. Polygenic obesity is caused by multiple factors, such as lack of exercise and excess food intake. In this study, we evaluated effects of 12 weeks of high-intensity interval training (HIIT) and isocratic moderate-intensity training (MIT) on anthropometric indice...
متن کاملThe effect of aerobic exercise on epicardial adipose tissue, insulin resistance, and some liver enzymes in high-fat diet-induced obesity male wistar rat
Background and Aim: Due to the prevalence and socio-economic consequences of obesity in mortality, cardiovascular (CAD) and nonalcoholic fatty liver disease the effectiveness of aerobic exercise on epicardial adipose tissue (EAT), insulin resistance (IR) and some liver enzymes of high-fat diet-induced obesity male wistar rats was investigated. Methods: Thirty-two male Wistar rats with an averag...
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ژورنال
عنوان ژورنال: INTERNATIONAL RESEARCH JOURNAL OF PHARMACY
سال: 2014
ISSN: 2230-8407
DOI: 10.7897/2230-8407.050209